Enabling technologies are those technologies preparing input data, analyzing output data and facilitating the whole processes for numerical simulations. This paper outlines current enabling technologies for large-scale multidisciplinary simulations used in the High End Digital Prototyping (HEDP) system, a problem solving environment equipped with capability of mesh generation and large-scale visualization. A problem solving environment is a computer system that provides all the computational facilities necessary to solve a target class of problems. Mesh generation continues to be the pacing technology for a practical numerical analysis, which is essential to yielding an accurate and efficient solution. Large-scale visualization maps the massive data to some kinds of scenes interactively, which can be realized through a tiled display wall system with distributed visualization capability. HEDP is designed for large-scale and multidisciplinary simulations, and there are four categories of modules involved, namely pre-processing module, computing module, post-processing module, and platform control module. All these modules are coupled through a software bus, which makes the modules integrated seamlessly. Detailed design principles and applications of the HEDP environment are addressed in this paper.