@Article{JFBI-6-23, author = {Budimir Mijovic and Ante Agic}, title = {Bio-inspired Electrospun Fibre Structures - Numerical Model}, journal = {Journal of Fiber Bioengineering and Informatics}, year = {2013}, volume = {6}, number = {1}, pages = {23--32}, abstract = {A systems approach that integrates processing, structure, property and performance relations has been used in the design of multilevel-structured fibrous materials. For electrospun fibrous structure, numerical implementation of multiscale materials philosophy provides a hierarchy of computational models defining design parameters that are integrated through computational continuum mechanics. Electrospun micro/nano (multiscale) poly(ε-caprolactone) (PCL) fibrous scaffolds were studied. The fibrous structures were evaluated for their mechanical, morphological and cell attachment properties. The cell attachment studies showed that cell activity on multi-scale scaffolds was higher compared to micro-fibrous scaffolds. These results suggest that the combination of a micro- and nano-fiber hierarchical scaffold could be more beneficial for tissue engineering applications than for individual scaffolds.}, issn = {2617-8699}, doi = {https://doi.org/10.3993/jfbi03201302}, url = {http://global-sci.org/intro/article_detail/jfbi/4818.html} }